Skeleton morphogenesis: Defining the skeletal elements
نویسنده
چکیده
The vertebrate skeleton consists of a variety of individual elements, each characterized by a specific size and shape. There are two main modes by which these skeletal elements are formed. In one mode, known as ‘intramembranous ossification’, which occurs for example in the development of the skull, mesenchymal cells directly differentiate into bone. In the other mode, known as ‘endochondral ossification’, which is used to form the bones of the vertebral column, the extremities and the shoulder and pelvic girdles, the skeletal elements are derived from cartilage precursors that are later replaced by bone tissue.
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عنوان ژورنال:
- Current Biology
دوره 7 شماره
صفحات -
تاریخ انتشار 1997